食品伙伴網(wǎng)訊   據(jù)歐盟食品安全局（EFSA）消息，3月20日歐盟食品安全局專家組就內(nèi)分泌干擾物質(zhì)的危害評估發(fā)布了意見。

    歐盟食品安全局專家組闡述了內(nèi)分泌干擾物質(zhì)的鑒定標準，內(nèi)分析干擾物質(zhì)對人體健康以及環(huán)境影響的現(xiàn)行測定方法。

    專家組認為，內(nèi)分泌干擾物質(zhì)可以按照以下3種方法鑒定：內(nèi)分泌活性、不良效應、內(nèi)分泌活性與不良效應之間可能的聯(lián)系。

    部分原文報道如下：

    Upon request of the European Commission, the Scientific Committee （SC） of the European Food Safety Authority reviewed existing information related to the testing and assessment of endocrine active substances （EASs） and endocrine disruptors （EDs）。 This work was conducted by a working group of experts in endocrinology, risk assessment and toxicology, together with observers from other EU agencies, namely EMA, ECHA and EEA. To distinguish between EDs and other groups of substances with different modes of action, it was concluded that an ED is defined by three criteria: the presence of i） an adverse effect in an intact organism or a （sub）population; ii） an endocrine activity; and iii） a plausible causal relationship between the two. As scientific criteria for adversity have not been generally defined, specific criteria for endocrine disrupting effects could not be identified.

    Hence, expert judgement is required to assess on a case-by-case basis the （eco）toxicological relevance of changes at the molecular to individual and/or （sub）population level following exposure to an EAS. The SC concluded that a reasonably complete suite of standardised assays for testing the effects of EASs is （or will soon be） available for the oestrogenic, androgenic, thyroid and steroidogenic modalities in mammals and fish, with fewer tests for birds and amphibians.

    原文鏈接：<http://www.efsa.europa.eu/en/efsajournal/pub/3132.htm>