食品伙伴網(wǎng)訊 2020年11月17日,歐盟食品安全局就一種食品酶磷脂酶A2(Phospholipase A2)的安全性評價(jià)發(fā)布意見。
據(jù)了解,這種食品酶是由AB Enzymes GmbH公司用轉(zhuǎn)基因里氏木霉(Trichoderma reesei)菌株 RF8793生產(chǎn)的,旨在用于油脂的脫膠和雞蛋改性卵磷脂的生產(chǎn)中。
經(jīng)過評估,專家小組認(rèn)為,在預(yù)期的使用條件下,不能排除通過飲食接觸引起過敏和誘發(fā)反應(yīng)的風(fēng)險(xiǎn),但可能性被認(rèn)為很低。由于TOS值是毒理學(xué)和暴露評估的基礎(chǔ),因此專家小組無法對轉(zhuǎn)基因里氏木霉菌株RF8793產(chǎn)生的食品酶磷脂酶A2進(jìn)行評估。部分原文報(bào)道如下:
The food enzyme phospholipase A2 (phosphatidylcholine 2‐acylhydrolase) is produced with the genetically modified Trichoderma reesei strain RF8793 by AB Enzymes GmbH. The genetic modifications do not give rise to safety concerns. The food enzyme is free from viable cells of the production organism and its DNA. The food enzyme is intended to be used in degumming of fats and oils and modified lecithin production from egg. Due to lack of data on the compositional parameters, total organic solids (TOS) values could not be calculated. For this reason, the representativeness of the batch used for toxicological examination could not be established and dietary exposure could not be calculated. The Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood is considered to be low. As TOS values form the basis of toxicological and exposure assessments, the Panel is not in a position to conclude its assessment of the food enzyme phospholipase A2 produced with the genetically modified Trichoderma reesei strain RF8793.?
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