食品伙伴網(wǎng)訊 據(jù)歐盟食品安全局(EFSA)消息,3月1日歐盟食品安全局專家組就重新評估專利藍V(Patent Blue V ,E 131)用作食品添加劑發(fā)布了意見。
歐盟專家組認為,按照專利藍V最大允許使用限量來看,學步幼兒與兒童的ADI值在5mg/kg bw/day之上。按照目前報告的最大使用限量來看,所有年齡群體的ADI值在5mg/kg bw/day以下。
部分原文報道如下:
The Panel on Food Additives and Nutrient Sources added to Food provides a scientific opinion re-evaluating the safety of Patent Blue V (E 131)。 Patent Blue V (E 131) is a triarylmethane dye permitted for use as a food additive in the EU, that has been previously evaluated by JECFA in 1970 and 1975 and the EU SCF in 1983; JECFA established a Temporary Acceptable Daily Intake (ADI) of 0-1 mg/kg bw/day in 1970, but withdrew it in 1975. Until now JECFA has not allocated an ADI to Patent Blue V (E 131)。 The SCF established an ADI of 0-15 mg/kg bw/day.
The Panel was not provided with a newly submitted dossier and based its evaluation on previous evaluations, additional literature that became available since then and the data available following a public call for data. The Panel concluded that the present dataset provides a rationale for a re-definition of the ADI. Using the NOAEL of 500 mg/kg bw/day derived from a chronic toxicity study in mice and applying an uncertainty factor of 100 to this NOAEL, the Panel establishes an ADI of 5 mg/kg bw/day.
The Panel noted that at the maximum permitted levels of use of Patent Blue V (E 131), exposure estimates for high consumers are above the ADI of 5 mg/kg bw/day in toddlers and children. At the maximum reported use levels of Patent Blue V (E 131), exposure estimates are below the ADI of 5 mg/kg bw/day for all groups of the population.
原文鏈接:<http://www.efsa.europa.eu/en/efsajournal/pub/2818.htm>