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當(dāng)前位置: 首頁 » 食品資訊 » 外訊導(dǎo)讀 » 歐盟評估由解脂耶氏酵母發(fā)酵生產(chǎn)的甜菊糖苷作為食品添加劑的安全性

歐盟評估由解脂耶氏酵母發(fā)酵生產(chǎn)的甜菊糖苷作為食品添加劑的安全性

放大字體  縮小字體 時(shí)間:2023-12-26 10:54 來源:食品伙伴網(wǎng) 作者: 澤夕   
核心提示:2023年12月20日,據(jù)歐盟食品安全局(EFSA)消息,歐盟食品添加劑和調(diào)味劑小組(FAF)就解脂耶氏酵母發(fā)酵生產(chǎn)的甜菊糖苷(steviol glycosides)作為食品添加劑的安全性發(fā)表科學(xué)意見。
   食品伙伴網(wǎng)訊  2023年12月20日,據(jù)歐盟食品安全局EFSA)消息,歐盟食品添加劑調(diào)味劑小組(FAF)就解脂耶氏酵母發(fā)酵生產(chǎn)的甜菊糖苷(steviol glycosides)作為食品添加劑的安全性發(fā)表科學(xué)意見。
 
  經(jīng)過評估,專家小組得出結(jié)論,在建議的用途和使用水平下,由解脂耶氏酵母發(fā)酵生產(chǎn)的甜菊糖苷作為食品添加劑不存在安全問題。部分原文報(bào)道如下:
 
  The EFSA Panel on Food Additive and Flavourings (FAF Panel) provides a scientific opinion on the safety of a new process to produce steviol glycosides by fermentation of simple sugars using a genetically modified strain of Yarrowia lipolytica (named Y. lipolytica VRM). The manufacturing process may result in impurities different from those that may be present in the other steviol glycosides E 960a-d, therefore the Panel concluded that separate specifications are required for the food additive produced as described in the current application. Viable cells and DNA from the production strain are not present in the final product. The Panel considered that the demonstration of the absence of kaurenoic acid in the proposed food additive, using a method with a limit of detection (LOD) of 0.3 mg/kg, is adequate to dispel the concerns for potential genotoxicity. Given that all steviol glycosides follow the same metabolic pathways, the Panel considered that the current steviol glycosides would fall within the same group of substances. Therefore, the Panel considered that the already existing data on rebaudioside M and structurally related steviol glycosides are sufficient, and a similar metabolic fate and toxicity is expected for the food additive. The results from the bacterial reverse mutation assay and the in vitro micronucleus assay were negative and indicated absence of genotoxicity from the food additive. The existing acceptable daily intake (ADI) of 4 mg/kg body weight (bw) per day, expressed as steviol equivalents, was considered to be applicable to the proposed food additive. The Panel concluded that there is no safety concern for steviol glycosides, predominantly Rebaudioside M, produced by fermentation using Y. lipolytica VRM, to be used as a food additive at the proposed uses and use levels.
 
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日期:2023-12-26
 

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