由大腸桿菌基因修飾菌株( CGMCC 7.232 )發(fā)酵產(chǎn)生的L-蘇氨用于所有動物物種的飼料和飲用水,在生產(chǎn)菌株的基因改造方面沒有引起任何安全問題,對用于特定物種以及消費(fèi)者也是安全的。但在沒有數(shù)據(jù)的情況下,歐盟食品安全局動物飼料專家組(FEEDAP)無法斷定添加劑對皮膚和眼睛有刺激性或是皮膚致敏的可能性。對于處理添加劑的人來說,有吸入接觸內(nèi)毒素的風(fēng)險。
部分原文報道如下:
The product subject of this assessment is l‐threonine produced by fermentation with a genetically modified strain of Escherichia coli (CGMCC 7.232)。 It is intended to be used in feed and water for drinking for all animal species and categories. The production strain and its recombinant DNA were not detected in the additive. The product l‐threonine, manufactured by fermentation with E. coli CGMCC 7.232, does not raise any safety concern with regard to the genetic modification of the production strain. l‐Threonine produced using E. coli CGMCC 7.232 is considered safe for the target species. The FEEDAP Panel has concerns regarding the safety of the simultaneous administration of l‐threonine via water for drinking and feed. l‐Threonine produced using E. coli CGMCC 7.232 is safe for the consumer. In absence of data, the FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and eyes or to be a skin sensitiser. There is a risk from the inhalation exposure to endotoxins for persons handling the additive. l‐Threonine produced using E. coli CGMCC 7.232 is safe for the environment. The product under assessment is considered an efficacious source of the amino acid l‐threonine for all animal species. For l‐threonine to be as efficacious in ruminants as in non‐ruminant species, it requires protection against degradation in the rumen.
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