食品伙伴網訊 據歐盟食品安全局(EFSA)消息,6月26日歐盟食品安全局就食品中的硝基呋喃及其代謝物發(fā)布意見。本次歐盟食品安全局評估了呋喃唑酮、呋喃它酮、呋喃咀啶、呋喃西林以及硝呋索爾類硝基呋喃。目前歐盟禁止硝基呋喃類抗菌劑用于產肉動物。然而呋喃唑酮、呋喃咀啶與呋喃西林可以用于人類。
歐盟食品安全局污染物專家組建議,根據目前的指南有必要開展SEM的致癌性研究,有必要了解SEM遺傳毒性與致癌效應的機理。
部分原文報道如下:
Nitrofurans are antimicrobial agents not authorised for use in food-producing animals in the European Union. Nitrofurans are rapidly metabolised, occurring in animal tissues as protein-bound metabolites. The European Commission requested EFSA to provide a scientific opinion on the risks to human health related to the presence of nitrofurans in food and whether a reference point for action (RPA) of 1.0 ?g/kg for the marker metabolites is adequate to protect public health. Data on occurrence of nitrofuran marker metabolites in food were extracted from the national residue monitoring plan results and from the Rapid Alert System for Food and Feed (RASFF)。 The CONTAM Panel concluded that these data were too limited to carry out a reliable human dietary exposure assessment. Instead, human dietary exposure was calculated for a scenario in which a single nitrofuran marker metabolite is present at 1.0 ?g/kg in foods of animal origin, excluding milk and dairy products.