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當(dāng)前位置: 首頁(yè) » 食品資訊 » 外訊導(dǎo)讀 » 歐盟評(píng)估牛乳骨橋蛋白作為新型食品的安全性

歐盟評(píng)估牛乳骨橋蛋白作為新型食品的安全性

放大字體  縮小字體 時(shí)間:2022-05-07 15:39 來(lái)源:食品伙伴網(wǎng) 作者: 澤夕   
核心提示:2022年5月6日,據(jù)歐盟食品安全局(EFSA)消息,歐盟營(yíng)養(yǎng)、新型食品和食物過(guò)敏原(NDA)研究小組就牛乳骨橋蛋白(bovine milk osteopontin)作為新型食品的安全性發(fā)表科學(xué)意見。
   食品伙伴網(wǎng)訊  2022年5月6日,據(jù)歐盟食品安全局EFSA)消息,歐盟營(yíng)養(yǎng)、新型食品和食物過(guò)敏原(NDA)研究小組就牛乳骨橋蛋白(bovine milk osteopontin)作為新型食品的安全性發(fā)表科學(xué)意見。
 
  經(jīng)過(guò)評(píng)估,專家小組得出結(jié)論,在建議的使用條件下,牛乳骨橋蛋白作為新型食品是安全的。部分原文報(bào)道如下:
 
  Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on bovine milk osteopontin (bmOPN) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF concerns OPN derived from bovine whey. The NF is intended to be used at a maximum use level of 151 mg/L, in infant formula (IF), follow-on formula (FoF) and ready-to-eat dairy-based meals for children up to 35 months of age. As compared to the concentrations naturally present in cow’s milk and concentrations found in IF on the market reported in the literature, the proposed use level of the NF represents an about 10-fold higher concentration of bmOPN. The intended use levels of the NF would provide bmOPN at a concentration within the range of human milk (hm) OPN. In a 6-month study, 14, 72 and 140 mg bmOPN/L in reconstituted (as consumed) IF were given to 279 infants in order to study possible effects on frequency and severity of adverse events, and growth, formula intake and stool consistency. Despite that a number of inconsistencies and limitations were noted in the study report, the Panel considers that the results obtained from this study do not raise safety concerns. Considering the source of the NF, that neither the toxicological studies nor the provided infant study do raise safety concerns, and the low bmOPN plasma levels in infants resulting from the consumption of the NF, the Panel considers that the margin of exposure (i.e. 36) between the NOAEL of the subchronic toxicity study (1,200 mg/kg bw per day) and the highest P95 estimate for infants (33.4 mg/kg bw per day) is sufficient. The Panel concludes that the NF is safe under the proposed conditions of use.
 
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日期:2022-05-07
 
 
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